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Toward a Molecular Classification of Colorectal Cancer: The Role of Microsatellite Instability Status

Microsatellite instability (MSI) is the molecular hallmark of DNA mismatch repair deficiency. Since its initial description in colorectal cancer (CRC) in 1993 and its association with Lynch syndrome, the most common inherited cancer predisposition world-wide, accumulating evidence suggests that MSI...

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Hlavní autor: Heinimann, Karl
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814007/
https://ncbi.nlm.nih.gov/pubmed/24199172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00272
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