IL-2 Immunotherapy Reveals Potential for Innate Beta Cell Regeneration in the Non-Obese Diabetic Mouse Model of Autoimmune Diabetes

Type-1 diabetes (T1D) is an autoimmune disease targeting insulin-producing beta cells, resulting in dependence on exogenous insulin. To date, significant efforts have been invested to develop immune-modulatory therapies for T1D treatment. Previously, IL-2 immunotherapy was demonstrated to prevent an...

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Autori principali: Diaz-de-Durana, Yaiza, Lau, Janet, Knee, Deborah, Filippi, Christophe, Londei, Marco, McNamara, Peter, Nasoff, Marc, DiDonato, Michael, Glynne, Richard, Herman, Ann E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813455/
https://ncbi.nlm.nih.gov/pubmed/24205242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078483
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