Polymorphisms of Glutathione S-Transferase Mu 1 (GSTM1), Theta 1 (GSTT1), and Pi 1 (GSTP1) Genes and Epithelial Ovarian Cancer Risk

Background: Exposure of ovarian cells to estrogen, which is detoxified by glutathione S-transferases (GSTs), has been associated with epithelial ovarian cancer (EOC) development. Objectives: We tested in this study whether the GSTM1, GSTT1 and GSTP1 Ile105Val polymorphisms alter the risk of EOC. Mat...

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Autores principales: Oliveira, Cristiane, Lourenço, Gustavo Jacob, Sagarra, Regina Aparecida Martinho, Derchain, Sophie Françoise Mauricette, Segalla, José Getulio, Lima, Carmen Silvia Passos
Formato: Artigo
Lenguaje:Inglês
Publicado: IOS Press 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810705/
https://ncbi.nlm.nih.gov/pubmed/22960333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/DMA-2012-0920
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