Glycyrrhetinic acid-modified chitosan nanoparticles enhanced the effect of 5-fluorouracil in murine liver cancer model via regulatory T-cells

Modified chitosan nanoparticles are a promising platform for drug, such as 5-fluorouracil (5-FU), gene, and vaccine delivery. Here, we used chitosan and hepatoma cell-specific binding molecule glycyrrhetinic acid (GA) to synthesize glycyrrhetinic acid-modified chitosan (GA-CTS). The synthetic produc...

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Autors principals: Cheng, Mingrong, Xu, Hongzhi, Wang, Yong, Chen, Houxiang, He, Bing, Gao, Xiaoyan, Li, Yingchun, Han, Jiang, Zhang, Zhiping
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2013
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810199/
https://ncbi.nlm.nih.gov/pubmed/24187487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S52809
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