The Viral Polymerase Inhibitor 2′-C-Methylcytidine Inhibits Norwalk Virus Replication and Protects against Norovirus-Induced Diarrhea and Mortality in a Mouse Model

Human noroviruses are a major cause of food-borne illness, accountable for 50% of all-etiologies outbreaks of acute gastroenteritis (in both developing and developed countries). There is no vaccine or antiviral drug for the prophylaxis or treatment of norovirus-induced gastroenteritis. We recently r...

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Bibliografiska uppgifter
Huvudupphovsmän: Rocha-Pereira, Joana, Jochmans, Dirk, Debing, Yannick, Verbeken, Erik, Nascimento, Maria S. J., Neyts, Johan
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2013
Ämnen:
Vaccines and Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807313/
https://ncbi.nlm.nih.gov/pubmed/23986582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02064-13
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