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Protective effect of P188 in the Model of Acute Trauma to Human Ankle Cartilage: the Mechanism of Action
OBJECTIVE: Since P188 poloxamer is effective in promoting cell survival in models of acute trauma the objectives were to understand the mechanism of its action focusing on GSK3 activation, IL-6 and p38 signaling. DESIGN: Sixteen normal human tali were impacted using 4mm diameter indenter with an imp...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3805249/ https://ncbi.nlm.nih.gov/pubmed/20736797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/BOT.0b013e3181ec4712 |
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