SMAD3 rs17228212 Gene Polymorphism Is Associated with Reduced Risk to Cerebrovascular Accidents and Subclinical Atherosclerosis in Anti-CCP Negative Spanish Rheumatoid Arthritis Patients

Rheumatoid arthritis (RA) is a complex polygenic inflammatory disease associated with accelerated atherosclerosis and increased risk of cardiovascular (CV) disease. Previous genome-wide association studies have described SMAD3 rs17228212 polymorphism as an important signal associated with CV events....

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Autori principali: García-Bermúdez, Mercedes, López-Mejías, Raquel, Genre, Fernanda, Castañeda, Santos, González-Juanatey, Carlos, Llorca, Javier, Corrales, Alfonso, Miranda-Filloy, José A., Rueda-Gotor, Javier, Gómez-Vaquero, Carmen, Rodríguez-Rodríguez, Luis, Fernández-Gutiérrez, Benjamín, Pascual-Salcedo, Dora, Balsa, Alejandro, López-Longo, Francisco J., Carreira, Patricia, Blanco, Ricardo, González-Álvaro, Isidoro, Martín, Javier, González-Gay, Miguel A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804609/
https://ncbi.nlm.nih.gov/pubmed/24204921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077695
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