Synergistic combination of valproic acid and oncolytic parvovirus H-1PV as a potential therapy against cervical and pancreatic carcinomas

The rat parvovirus H-1PV has oncolytic and tumour-suppressive properties potentially exploitable in cancer therapy. This possibility is being explored and results are encouraging, but it is necessary to improve the oncotoxicity of the virus. Here we show that this can be achieved by co-treating canc...

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Autors principals: Li, Junwei, Bonifati, Serena, Hristov, Georgi, Marttila, Tiina, Valmary-Degano, Séverine, Stanzel, Sven, Schnölzer, Martina, Mougin, Christiane, Aprahamian, Marc, Grekova, Svitlana P, Raykov, Zahari, Rommelaere, Jean, Marchini, Antonio
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2013
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799578/
https://ncbi.nlm.nih.gov/pubmed/24092664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201302796
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