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A novel epigenetic CREB-miR-373 axis mediates ZIP4-induced pancreatic cancer growth

Changes in the intracellular levels of the essential micronutrient zinc have been implicated in multiple diseases including pancreatic cancer; however, the molecular mechanism is poorly understood. Here, we report a novel mechanism where increased zinc mediated by the zinc importer ZIP4 transcriptio...

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Autori principali: Zhang, Yuqing, Yang, Jingxuan, Cui, Xiaobo, Chen, Yong, Zhu, Vivian F, Hagan, John P, Wang, Huamin, Yu, Xianjun, Hodges, Sally E, Fang, Jing, Chiao, Paul J, Logsdon, Craig D, Fisher, William E, Brunicardi, F Charles, Chen, Changyi, Yao, Qizhi, Fernandez-Zapico, Martin E, Li, Min
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799489/
https://ncbi.nlm.nih.gov/pubmed/23857777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201302507
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