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Irx3 and Pax6 establish differential competence for Shh-mediated induction of GABAergic and glutamatergic neurons of the thalamus

During embryonic development, the presumptive GABAergic rostral thalamus (rTh) and glutamatergic caudal thalamus (cTh) are induced by Sonic hedgehog (Shh) signaling from the zona limitans intrathalamica (ZLI) at the rostral border of the thalamic primordium. We found that these inductions are limite...

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Detalhes bibliográficos
Main Authors: Robertshaw, Ellen, Matsumoto, Ken, Lumsden, Andrew, Kiecker, Clemens
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799351/
https://ncbi.nlm.nih.gov/pubmed/24065827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304311110
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