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HIV-1 Infection of T Cells and Macrophages Are Differentially Modulated by Virion-Associated Hck: A Nef-Dependent Phenomenon

The proline repeat motif (PxxP) of Nef is required for interaction with the SH3 domains of macrophage-specific Src kinase Hck. However, the implication of this interaction for viral replication and infectivity in macrophages and T lymphocytes remains unclear. Experiments in HIV-1 infected macrophage...

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Bibliografiska uppgifter
Huvudupphovsmän: Cornall, Alyssa, Mak, Johnson, Greenway, Alison, Tachedjian, Gilda
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798898/
https://ncbi.nlm.nih.gov/pubmed/24051604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v5092235
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