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Overexpression of the Transcriptional Repressor Complex BCL-6/BCoR Leads to Nuclear Aggregates Distinct from Classical Aggresomes

Nuclear inclusions of aggregated proteins have primarily been characterized for molecules with aberrant poly-glutamine repeats and for mutated or structurally altered proteins. They were termed “nuclear aggresomes” and misfolding was shown to promote association with molecular chaperones and proteas...

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Autores principales: Buchberger, Elisabeth, El Harchi, Miriam, Payrhuber, Dietmar, Zommer, Anna, Schauer, Dominic, Simonitsch-Klupp, Ingrid, Bilban, Martin, Brostjan, Christine
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795655/
https://ncbi.nlm.nih.gov/pubmed/24146931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076845
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