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Selective ablation of mast cells or basophils reduces peanut-induced anaphylaxis in mice

BACKGROUND: Studies using c-kit mutant mast cell (MC)-deficient mice and antibody-mediated depletion of basophils suggest that both MCs and basophils can contribute to peanut-induced anaphylaxis (PIA). However, interpretation of data obtained using such approaches is complicated because c-kit mutant...

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Bibliographic Details
Main Authors: Reber, Laurent L., Marichal, Thomas, Mukai, Kaori, Kita, Yoshihiro, Tokuoka, Suzumi M., Roers, Axel, Hartmann, Karin, Karasuyama, Hajime, Nadeau, Kari C., Tsai, Mindy, Galli, Stephen J.
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794715/
https://ncbi.nlm.nih.gov/pubmed/23915716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2013.06.008
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