Regulation of human hematopoietic stem cell self-renewal by the microenvironment’s control of retinoic acid signaling

The high expression of aldehyde dehydrogenase 1, also known as retinaldehyde dehydrogenase, by hematopoietic stem cells (HSCs) suggests an important role for retinoic acid (RA) signaling in determining the fate of these cells. We found that primitive human bone marrow-derived CD34(+)CD38(−) cells no...

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Huvudupphovsmän: Ghiaur, Gabriel, Yegnasubramanian, Srinivasan, Perkins, Brandy, Gucwa, Jessica L., Gerber, Jonathan M., Jones, Richard J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2013
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791732/
https://ncbi.nlm.nih.gov/pubmed/24043786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305937110
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