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Genetic Mapping with Multiple Levels of Phenotypic Information Reveals Determinants of Lymphocyte Glucocorticoid Sensitivity
Clinical response to glucocorticoids, steroid hormones widely used as pharmaceuticals, varies extensively in that many individuals (∼30%) show a weak response to treatment. Although little is known about the molecular basis of this variation, regulatory polymorphisms are likely to play a key role gi...
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Główni autorzy: | , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
Elsevier
2013
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3791266/ https://ncbi.nlm.nih.gov/pubmed/24055111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.08.005 |
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