Genetic Mapping with Multiple Levels of Phenotypic Information Reveals Determinants of Lymphocyte Glucocorticoid Sensitivity

Clinical response to glucocorticoids, steroid hormones widely used as pharmaceuticals, varies extensively in that many individuals (∼30%) show a weak response to treatment. Although little is known about the molecular basis of this variation, regulatory polymorphisms are likely to play a key role gi...

Full description

Saved in:
Bibliographic Details
Main Authors: Maranville, Joseph C., Baxter, Shaneen S., Witonsky, David B., Chase, Meredith A., Di Rienzo, Anna
Format: Artigo
Language:Inglês
Published: Elsevier 2013
Subjects:
Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791266/
https://ncbi.nlm.nih.gov/pubmed/24055111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.08.005
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items