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Mean overall survival gain with aflibercept plus FOLFIRI vs placebo plus FOLFIRI in patients with previously treated metastatic colorectal cancer

BACKGROUND: Mean survival in cancer trials can be estimated with statistical techniques to extrapolate study survival curves. This methodology was applied to data from the VELOUR trial, where use of the novel biologic aflibercept (ziv-aflibercept in the United States) in combination with fluorouraci...

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Main Authors: Joulain, F, Proskorovsky, I, Allegra, C, Tabernero, J, Hoyle, M, Iqbal, S U, Van Cutsem, E
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790175/
https://ncbi.nlm.nih.gov/pubmed/24045663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.523
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