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Widespread purifying selection on RNA structure in mammals
Evolutionarily conserved RNA secondary structures are a robust indicator of purifying selection and, consequently, molecular function. Evaluating their genome-wide occurrence through comparative genomics has consistently been plagued by high false-positive rates and divergent predictions. We present...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3783177/ https://ncbi.nlm.nih.gov/pubmed/23847102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt596 |
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