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CREATING A “PRO-SURVIVAL” PHENOTYPE THROUGH EPIGENETIC MODULATION
BACKGROUND: We have recently demonstrated that treatment with suberoylanilide hydroxamic acid (SAHA), a histone deacetylase inhibitor, significantly improves survival in a rodent model of lipopolysaccharide (LPS)-induced endotoxic shock. However, the precise mechanisms have not been well defined. Th...
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| Główni autorzy: | , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3782099/ https://ncbi.nlm.nih.gov/pubmed/22938904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2012.06.036 |
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