Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription

Recent studies suggest a hierarchical model in which lineage-determining factors act in a collaborative manner to select and prime cell-specific enhancers, thereby enabling signal-dependent transcription factors to bind and function in a cell type-specific manner. Consistent with this model, TLR4 si...

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Main Authors: Kaikkonen, Minna U, Spann, Nathanael, Heinz, Sven, Romanoski, Casey E., Allison, Karmel A., Stender, Joshua D., Chun, Hyun B., Tough, David F., Prinjha, Rab K., Benner, Christopher, Glass, Christopher K.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779836/
https://ncbi.nlm.nih.gov/pubmed/23932714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.07.010
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