Action potential wavelength restitution predicts alternans and arrhythmia in murine Scn5a(+/−) hearts

Reductions in cardiac action potential wavelength, and the consequent wavebreak, have been implicated in arrhythmogenesis. Tachyarrhythmias are more common in the Brugada syndrome, particularly following pharmacological challenge, previously modelled using Scn5a(+/−) murine hearts. Propagation laten...

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Autors principals: Matthews, Gareth D K, Guzadhur, Laila, Sabir, Ian N, Grace, Andrew A, Huang, Christopher L-H
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2013
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779110/
https://ncbi.nlm.nih.gov/pubmed/23836691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.254938
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