Action potential wavelength restitution predicts alternans and arrhythmia in murine Scn5a(+/−) hearts

Reductions in cardiac action potential wavelength, and the consequent wavebreak, have been implicated in arrhythmogenesis. Tachyarrhythmias are more common in the Brugada syndrome, particularly following pharmacological challenge, previously modelled using Scn5a(+/−) murine hearts. Propagation laten...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Matthews, Gareth D K, Guzadhur, Laila, Sabir, Ian N, Grace, Andrew A, Huang, Christopher L-H
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2013
Sujets:
Research Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779110/
https://ncbi.nlm.nih.gov/pubmed/23836691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.254938
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