Leptin antagonist ameliorates chronic colitis in IL-10(−/−) mice

BACKGROUND: Although the etiology of two major forms of inflammatory bowel disease (IBD), Crohn’s disease (CD) and ulcerative colitis (UC) are unknown and evidence suggests that chronic intestinal inflammation is caused by an excessive immune response to mucosal antigens. Previous studies support th...

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Autors principals: Singh, Udai P., Singh, Narendra P., Guan, Hongbing, Busbee, Brandon, Price, Robert L., Taub, Dennis D., Mishra, Manoj K., Fayad, Raja, Nagarkatti, Mitzi, Nagarkatti, Prakash S.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778116/
https://ncbi.nlm.nih.gov/pubmed/23726523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2013.04.020
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