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Maternal Depletion of Piwi, a Component of the RNAi System, Impacts Heterochromatin Formation in Drosophila

A persistent question in epigenetics is how heterochromatin is targeted for assembly at specific domains, and how that chromatin state is faithfully transmitted. Stable heterochromatin is necessary to silence transposable elements (TEs) and maintain genome integrity. Both the RNAi system and heteroc...

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Main Authors: Gu, Tingting, Elgin, Sarah C. R.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777992/
https://ncbi.nlm.nih.gov/pubmed/24068954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003780
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