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Maternal Depletion of Piwi, a Component of the RNAi System, Impacts Heterochromatin Formation in Drosophila

A persistent question in epigenetics is how heterochromatin is targeted for assembly at specific domains, and how that chromatin state is faithfully transmitted. Stable heterochromatin is necessary to silence transposable elements (TEs) and maintain genome integrity. Both the RNAi system and heteroc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gu, Tingting, Elgin, Sarah C. R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777992/
https://ncbi.nlm.nih.gov/pubmed/24068954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003780
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