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Maternal Depletion of Piwi, a Component of the RNAi System, Impacts Heterochromatin Formation in Drosophila

A persistent question in epigenetics is how heterochromatin is targeted for assembly at specific domains, and how that chromatin state is faithfully transmitted. Stable heterochromatin is necessary to silence transposable elements (TEs) and maintain genome integrity. Both the RNAi system and heteroc...

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Autors principals: Gu, Tingting, Elgin, Sarah C. R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777992/
https://ncbi.nlm.nih.gov/pubmed/24068954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003780
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