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CD4(+) T-cell Responses Among Adults and Young Children In Response to Streptococcus pneumoniae and Haemophilus influenzae Vaccine Candidate Protein Antigens

We characterized cytokine profiles of CD4(+) T-helper (h) cells in adults and young children to ascertain if responses occur to next-generation candidate vaccine antigens PspA, PcpA, PhtD, PhtE, Ply, LytB of Streptococcus pneumonia (Spn) and Protein D and OMP26 of non-typeable Haemophilus influenzae...

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Bibliographic Details
Main Authors: Sharma, Sharad K., Roumanes, David, Almudevar, Anthony, Mosmann, Tim R., Pichichero, Michael E.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777711/
https://ncbi.nlm.nih.gov/pubmed/23632305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.03.060
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