Induction of retinol-binding protein 4 and placenta-specific 8 expression in human prostate cancer cells remaining in bone following osteolytic tumor growth inhibition by osteoprotegerin

New drugs that inhibit the osteoprotegerin (OPG)/receptor activator of NF-κB ligand (RANKL)/RANK pathway have demonstrated efficacy for the treatment of bone metastasis. Toxicities induced by these drugs, however, including osteonecrosis of the jaw and hypocalcemia, may adversely affect therapy. The...

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Bibliographic Details
Main Authors: UEHARA, HISANORI, TAKAHASHI, TETSUYUKI, IZUMI, KEISUKE
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2013
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775580/
https://ncbi.nlm.nih.gov/pubmed/23708710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2013.1954
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