Identification of Niemann-Pick C1 disease biomarkers through sphingolipid profiling

Niemann-Pick type C (NPC)1 is a rare neurodegenerative disease for which treatment options are limited. A major barrier to development of effective treatments has been the lack of validated biomarkers to monitor disease progression or serve as outcome measures in clinical trials. Using targeted meta...

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Hauptverfasser: Fan, Martin, Sidhu, Rohini, Fujiwara, Hideji, Tortelli, Brett, Zhang, Jessie, Davidson, Cristin, Walkley, Steven U., Bagel, Jessica H., Vite, Charles, Yanjanin, Nicole M., Porter, Forbes D., Schaffer, Jean E., Ory, Daniel S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2013
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770093/
https://ncbi.nlm.nih.gov/pubmed/23881911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M040618
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