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Mechanical Ventilation Enhances HMGB1 Expression in an LPS-Induced Lung Injury Model

BACKGROUND: Mechanical ventilation (MV) can augment inflammatory response in lipopolysaccharide (LPS) challenged lungs. High mobility group box 1 protein (HMGB1) is a pro-inflammatory mediator in ventilator-induced lung injury, but its mechanisms are not well defined. This study investigated the rol...

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Detalhes bibliográficos
Main Authors: Ding, Ning, Wang, Fang, Xiao, Hui, Xu, Lixin, She, Shouzhang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769250/
https://ncbi.nlm.nih.gov/pubmed/24058610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074633
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