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Differential Effect of Actomyosin Relaxation on the Dynamic Properties of Focal Adhesion Proteins

Treatment of cultured cells with inhibitors of actomyosin contractility induces rapid deterioration of stress fibers, and disassembly of the associated focal adhesions (FAs). In this study, we show that treatment with the Rho kinase inhibitor Y-27632, which blocks actomyosin contractility, induces d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lavelin, Irena, Wolfenson, Haguy, Patla, Israel, Henis, Yoav I., Medalia, Ohad, Volberg, Tova, Livne, Ariel, Kam, Zvi, Geiger, Benjamin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767655/
https://ncbi.nlm.nih.gov/pubmed/24039980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073549
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