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Cardiac angiogenesis directed by stable Hypoxia Inducible Factor-1
BACKGROUND: The heterodimeric, oxygen-sensitive transcription factor Hypoxia Inducible Factor-1 (HIF-1) orchestrates angiogenesis and plays a key role in the response to ischemia and the growth of cancers. METHODS: We developed a transgenic mouse line in which expression of an oxygen-stable HIF-1α c...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3766207/ https://ncbi.nlm.nih.gov/pubmed/23987100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-824X-5-15 |
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