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Optimisation of the foot-and-mouth disease virus 2A co-expression system for biomedical applications

BACKGROUND: Many biomedical applications require the expression or production of therapeutic hetero-multimeric proteins/protein complexes: in most cases only accomplished by co-ordinated co-expression within the same cell. Foot-and-mouth disease virus 2A (F2A) and ‘2A-like’ sequences are now widely...

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Autors principals: Minskaia, Ekaterina, Nicholson, John, Ryan, Martin D
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765190/
https://ncbi.nlm.nih.gov/pubmed/23968294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-13-67
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