High-Dose Intravenous Methylprednisolone for Hantavirus Cardiopulmonary Syndrome in Chile: A Double-Blind, Randomized Controlled Clinical Trial

Background. Andes virus (ANDV)–related hantavirus cardiopulmonary syndrome (HCPS) has a 35% case fatality rate in Chile and no specific treatment. In an immunomodulatory approach, we evaluated the efficacy of intravenous methylprednisolone for HCPS treatment, through a parallel-group, placebo-contro...

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Huvudupphovsmän: Vial, Pablo A., Valdivieso, Francisca, Ferres, Marcela, Riquelme, Raul, Rioseco, M. Luisa, Calvo, Mario, Castillo, Constanza, Díaz, Ricardo, Scholz, Luis, Cuiza, Analia, Belmar, Edith, Hernandez, Carla, Martinez, Jessica, Lee, Sang-Joon, Mertz, Gregory J., Abarca, Juan, Tomicic, Vinko, Aracena, M. Eugenia, Rehbein, Ana Maria, Velásquez, Soledad, Lavin, Victoria, Garrido, Felipe, Godoy, Paula, Martinez, Constanza, Chamorro, Juan Carlos, Contreras, Jorge, Hernandez, Jury, Pino, Marcelo, Villegas, Paola, Zapata, Viviana, León, Marisol, Vega, Ivonne, Otarola, Irisol, Ortega, Carlos, Daube, Elizabeth, Huecha, Doris, Neira, Alda, Ruiz, Ines, Nuñez, M. Antonieta, Monsalve, Luz, Chabouty, Henriette, Riquelme, Lorena, Palma, Samia, Bustos, Raul, Miranda, Ruben, Mardones, Jovita, Hernandez, Nora, Betancur, Yasna, Sanhueza, Ligia, Inostroza, Jaime, Donoso, Solange, Navarrete, Maritza, Acuña, Lily, Manriquez, Paulina, Castillo, Fabiola, Unzueta, Paola, Aguilera, Teresa, Osorio, Carola, Yobanolo, Veronica, Mardones, Jorge, Aranda, Sandra, Carvajal, Soledad, Sandoval, Moisés, Daza, Soraya, Vargas, Felipe, Diaz, Violeta, Riquelme, Mauricio, Muñoz, Miriam, Carriel, Andrea, Lanino, Paola, Hernandez, Susana, Schumacher, Patricia, Yañez, Lia, Marco, Claudia, Ehrenfeld, Mildred, Delgado, Iris, Rios, Susana, Vial, Cecilia, Bedrick, Edward
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2013
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Articles and Commentaries
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765009/
https://ncbi.nlm.nih.gov/pubmed/23784924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/cit394
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