High-Dose Intravenous Methylprednisolone for Hantavirus Cardiopulmonary Syndrome in Chile: A Double-Blind, Randomized Controlled Clinical Trial

Background. Andes virus (ANDV)–related hantavirus cardiopulmonary syndrome (HCPS) has a 35% case fatality rate in Chile and no specific treatment. In an immunomodulatory approach, we evaluated the efficacy of intravenous methylprednisolone for HCPS treatment, through a parallel-group, placebo-contro...

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Главные авторы: Vial, Pablo A., Valdivieso, Francisca, Ferres, Marcela, Riquelme, Raul, Rioseco, M. Luisa, Calvo, Mario, Castillo, Constanza, Díaz, Ricardo, Scholz, Luis, Cuiza, Analia, Belmar, Edith, Hernandez, Carla, Martinez, Jessica, Lee, Sang-Joon, Mertz, Gregory J., Abarca, Juan, Tomicic, Vinko, Aracena, M. Eugenia, Rehbein, Ana Maria, Velásquez, Soledad, Lavin, Victoria, Garrido, Felipe, Godoy, Paula, Martinez, Constanza, Chamorro, Juan Carlos, Contreras, Jorge, Hernandez, Jury, Pino, Marcelo, Villegas, Paola, Zapata, Viviana, León, Marisol, Vega, Ivonne, Otarola, Irisol, Ortega, Carlos, Daube, Elizabeth, Huecha, Doris, Neira, Alda, Ruiz, Ines, Nuñez, M. Antonieta, Monsalve, Luz, Chabouty, Henriette, Riquelme, Lorena, Palma, Samia, Bustos, Raul, Miranda, Ruben, Mardones, Jovita, Hernandez, Nora, Betancur, Yasna, Sanhueza, Ligia, Inostroza, Jaime, Donoso, Solange, Navarrete, Maritza, Acuña, Lily, Manriquez, Paulina, Castillo, Fabiola, Unzueta, Paola, Aguilera, Teresa, Osorio, Carola, Yobanolo, Veronica, Mardones, Jorge, Aranda, Sandra, Carvajal, Soledad, Sandoval, Moisés, Daza, Soraya, Vargas, Felipe, Diaz, Violeta, Riquelme, Mauricio, Muñoz, Miriam, Carriel, Andrea, Lanino, Paola, Hernandez, Susana, Schumacher, Patricia, Yañez, Lia, Marco, Claudia, Ehrenfeld, Mildred, Delgado, Iris, Rios, Susana, Vial, Cecilia, Bedrick, Edward
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765009/
https://ncbi.nlm.nih.gov/pubmed/23784924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/cit394
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