High-Dose Intravenous Methylprednisolone for Hantavirus Cardiopulmonary Syndrome in Chile: A Double-Blind, Randomized Controlled Clinical Trial

Background. Andes virus (ANDV)–related hantavirus cardiopulmonary syndrome (HCPS) has a 35% case fatality rate in Chile and no specific treatment. In an immunomodulatory approach, we evaluated the efficacy of intravenous methylprednisolone for HCPS treatment, through a parallel-group, placebo-contro...

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Main Authors: Vial, Pablo A., Valdivieso, Francisca, Ferres, Marcela, Riquelme, Raul, Rioseco, M. Luisa, Calvo, Mario, Castillo, Constanza, Díaz, Ricardo, Scholz, Luis, Cuiza, Analia, Belmar, Edith, Hernandez, Carla, Martinez, Jessica, Lee, Sang-Joon, Mertz, Gregory J., Abarca, Juan, Tomicic, Vinko, Aracena, M. Eugenia, Rehbein, Ana Maria, Velásquez, Soledad, Lavin, Victoria, Garrido, Felipe, Godoy, Paula, Martinez, Constanza, Chamorro, Juan Carlos, Contreras, Jorge, Hernandez, Jury, Pino, Marcelo, Villegas, Paola, Zapata, Viviana, León, Marisol, Vega, Ivonne, Otarola, Irisol, Ortega, Carlos, Daube, Elizabeth, Huecha, Doris, Neira, Alda, Ruiz, Ines, Nuñez, M. Antonieta, Monsalve, Luz, Chabouty, Henriette, Riquelme, Lorena, Palma, Samia, Bustos, Raul, Miranda, Ruben, Mardones, Jovita, Hernandez, Nora, Betancur, Yasna, Sanhueza, Ligia, Inostroza, Jaime, Donoso, Solange, Navarrete, Maritza, Acuña, Lily, Manriquez, Paulina, Castillo, Fabiola, Unzueta, Paola, Aguilera, Teresa, Osorio, Carola, Yobanolo, Veronica, Mardones, Jorge, Aranda, Sandra, Carvajal, Soledad, Sandoval, Moisés, Daza, Soraya, Vargas, Felipe, Diaz, Violeta, Riquelme, Mauricio, Muñoz, Miriam, Carriel, Andrea, Lanino, Paola, Hernandez, Susana, Schumacher, Patricia, Yañez, Lia, Marco, Claudia, Ehrenfeld, Mildred, Delgado, Iris, Rios, Susana, Vial, Cecilia, Bedrick, Edward
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2013
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Articles and Commentaries
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765009/
https://ncbi.nlm.nih.gov/pubmed/23784924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/cit394
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