BAD Dephosphorylation and Decreased Expression of MCL-1 Induce Rapid Apoptosis in Prostate Cancer Cells

PTEN loss and constitutive activation of the PI3K signaling pathway have been associated with advanced androgen-independent prostate cancer. PTEN-deficient prostate cancer C42Luc cells survive in serum-free media and show relative resistance to apoptosis even in the presence of the PI3K inhibitor ZS...

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Hauptverfasser: Yancey, Dana, Nelson, Kyle C., Baiz, Daniele, Hassan, Sazzad, Flores, Anabel, Pullikuth, Ashok, Karpova, Yelena, Axanova, Linara, Moore, Victoria, Sui, Guangchao, Kulik, George
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764099/
https://ncbi.nlm.nih.gov/pubmed/24040284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074561
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