Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 β-cell line

Recently, a novel type 1 diabetes association locus was identified at human chromosome 6p31.3, and transcription factor 19 (TCF19) is a likely causal gene. Little is known about Tcf19, and we now show that it plays a role in both proliferation and apoptosis in insulinoma cells. Tcf19 is expressed in...

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Auteurs principaux: Krautkramer, Kimberly A., Linnemann, Amelia K., Fontaine, Danielle A., Whillock, Amy L., Harris, Ted W., Schleis, Gregory J., Truchan, Nathan A., Marty-Santos, Leilani, Lavine, Jeremy A., Cleaver, Ondine, Kimple, Michelle E., Davis, Dawn Belt
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2013
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761170/
https://ncbi.nlm.nih.gov/pubmed/23860123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00147.2013
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