Pharmacokinetic interactions of CEP-1347 and atazanavir in HIV-infected patients

CEP-1347 is a potent inhibitor of mixed lineage kinase (MLK), which was investigated for ameliorating HIV-associated neurocognitive disorders. CEP-1347 and atazanavir pharmacokinetics were determined when CEP-1347 50 mg twice daily was administered to HIV-infected patients (n=20) receiving combinati...

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Main Authors: Ma, Qing, Gelbard, Harris A., Maggirwar, Sanjay B., Dewhurst, Stephen, Gendelman, Howard E., Peterson, Derick R., DiFrancesco, Robin, Hochreiter, Jill S., Morse, Gene D., Schifitto, Giovanni
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760277/
https://ncbi.nlm.nih.gov/pubmed/23737347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-013-0172-z
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