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Invariant NKT cell activation induces neutrophil accumulation and hepatitis: oppositely regulated by IL-4 and IFN-γ

Alpha-Galactosylceramide (α-Galcer), a specific agonist for invariant natural killer T (iNKT) cells, is being evaluated in clinical trials for the treatment of viral hepatitis and liver cancer. However, the results from α-Galcer treatment are mixed, partially because of the variety of cytokines prod...

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Main Authors: Wang, Hua, Feng, Dechun, Park, Ogyi, Yin, Shi, Gao, Bin
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758807/
https://ncbi.nlm.nih.gov/pubmed/23686838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26471
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