Effect of distance between decaying (125)I and DNA on Auger-electron induced double-strand break yield

PURPOSE: To determine the possible effects of (125)I-to-DNA distance on the magnitude and mechanism of Auger-electron induced-double-strand break (DSB) production. MATERIALS AND METHODS: We have synthesized a series of (125)I-labeled Hoechst (H) derivatives ((125)IE–H, (125)IB-H, (125)I-C(8)-H and (...

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Hlavní autoři: Balagurumoorthy, Pichumani, Xu, Xiang, Wang, Ketai, Adelstein, S. James, Kassis, Amin I.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755766/
https://ncbi.nlm.nih.gov/pubmed/22732063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/09553002.2012.706360
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