Flaviviruses Are Sensitive to Inhibition of Thymidine Synthesis Pathways

Dengue virus has emerged as a global health threat to over one-third of humankind. As a positive-strand RNA virus, dengue virus relies on the host cell metabolism for its translation, replication, and egress. Therefore, a better understanding of the host cell metabolic pathways required for dengue v...

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Autores principales: Fischer, Matthew A., Smith, Jessica L., Shum, David, Stein, David A., Parkins, Christopher, Bhinder, Bhavneet, Radu, Constantin, Hirsch, Alec J., Djaballah, Hakim, Nelson, Jay A., Früh, Klaus
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754125/
https://ncbi.nlm.nih.gov/pubmed/23824813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00101-13
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