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Previous History of Chronic Stress Changes the Transcriptional Response to Glucocorticoid Challenge in the Dentate Gyrus Region of the Male Rat Hippocampus

Chronic stress is a risk factor for several neuropsychiatric diseases, such as depression and psychosis. In response to stress glucocorticoids (GCs) are secreted that bind to mineralocorticoid and glucocorticoid receptors, ligand-activated transcription factors that regulate the transcription of gen...

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Detalhes bibliográficos
Main Authors: Datson, Nicole A., van den Oever, Jessica M.E., Korobko, Oksana B., Magarinos, Ana Maria, de Kloet, E. Ronald, McEwen, Bruce S.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749472/
https://ncbi.nlm.nih.gov/pubmed/23633533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-2233
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