An Intronic Variant in OPRD1 Predicts Treatment Outcome for Opioid Dependence in African-Americans

Although buprenorphine and methadone are both effective treatments for opioid dependence, their efficacy can vary significantly among patients. Genetic differences may explain some of the variability in treatment outcome. Understanding the interactions between genetic background and pharmacotherapy...

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Main Authors: Crist, Richard C, Clarke, Toni-Kim, Ang, Alfonso, Ambrose-Lanci, Lisa M, Lohoff, Falk W, Saxon, Andrew J, Ling, Walter, Hillhouse, Maureen P, Bruce, R Douglas, Woody, George, Berrettini, Wade H
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746708/
https://ncbi.nlm.nih.gov/pubmed/23612435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.99
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