Genetic variants in the folate pathway and risk of childhood acute lymphoblastic leukemia

OBJECTIVE: Folate is involved in the one-carbon metabolism that plays an essential role in the synthesis, repair and methylation of DNA. We examined whether child’s germline genetic variation in the folate pathway is associated with childhood acute lymphoblastic leukemia (ALL), and whether periconce...

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Detalhes bibliográficos
Main Authors: Metayer, Catherine, Scélo, Ghislaine, Chokkalingam, Anand P., Barcellos, Lisa F., Aldrich, Melinda C., Chang, Jeffrey S., Guha, Neela, Urayama, Kevin Y., Hansen, Helen M., Block, Gladys, Kiley, Vincent, Wiencke, John K., Wiemels, Joseph L., Buffler, Patricia A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744066/
https://ncbi.nlm.nih.gov/pubmed/21748308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10552-011-9795-7
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