A Core Human Primary Tumor Angiogenesis Signature Identifies the Endothelial Orphan Receptor ELTD1 as a Key Regulator of Angiogenesis

Limited clinical benefits derived from anti-VEGF therapy have driven the identification of new targets involved in tumor angiogenesis. Here, we report an integrative meta-analysis to define the transcriptional program underlying angiogenesis in human cancer. This approach identified ELTD1, an orphan...

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Main Authors: Masiero, Massimo, Simões, Filipa Costa, Han, Hee Dong, Snell, Cameron, Peterkin, Tessa, Bridges, Esther, Mangala, Lingegowda S., Wu, Sherry Yen-Yao, Pradeep, Sunila, Li, Demin, Han, Cheng, Dalton, Heather, Lopez-Berestein, Gabriel, Tuynman, Jurriaan B., Mortensen, Neil, Li, Ji-Liang, Patient, Roger, Sood, Anil K., Banham, Alison H., Harris, Adrian L., Buffa, Francesca M.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743050/
https://ncbi.nlm.nih.gov/pubmed/23871637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2013.06.004
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