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Genetic Architecture of Reciprocal CNVs

Copy number variants (CNVs) represent a frequent type of lesion in human genetic disorders that typically affects numerous genes simultaneously. This has raised the challenge of understanding which genes within a CNV drive clinical phenotypes. Although CNVs can arise by multiple mechanisms, a subset...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Golzio, Christelle, Katsanis, Nicholas
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740179/
https://ncbi.nlm.nih.gov/pubmed/23747035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2013.04.013
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