The opening of maitotoxin-sensitive calcium channels induces the acrosome reaction in human spermatozoa: differences from the zona pellucida

The acrosome reaction (AR), an absolute requirement for spermatozoa and egg fusion, requires the influx of Ca(2+) into the spermatozoa through voltage-dependent Ca(2+) channels and store-operated channels. Maitotoxin (MTx), a Ca(2+)-mobilizing agent, has been shown to be a potent inducer of the mous...

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Dettagli Bibliografici
Autori principali: Chávez, Julio C, de Blas, Gerardo A, de la Vega-Beltrán, José L, Nishigaki, Takuya, Chirinos, Mayel, González-González, María Elena, Larrea, Fernando, Solís, Alejandra, Darszon, Alberto, Treviño, Claudia L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739404/
https://ncbi.nlm.nih.gov/pubmed/20835262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2010.80
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