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Indole/triazole conjugates are selective inhibitors and inducers of bacterial biofilms

Herein is described a method of accessing indole/triazole and benzothiophene/triazole analogues that selectively promote or inhibit biofilm formation by Gram-positive and Gram-negative bacteria. Structure/function studies revealed that the addition of a bromine atom at the 2-position of the indole/t...

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Bibliographic Details
Main Authors: Minvielle, Marine J., Bunders, Cynthia A., Melander, Christian
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733276/
https://ncbi.nlm.nih.gov/pubmed/23930199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3MD00064H
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