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A Cryptic TOG Domain with a Distinct Architecture Underlies CLASP- Dependent Bipolar Spindle Formation
CLASP is a key regulator of microtubule (MT) dynamics and bipolar mitotic spindle structure with CLASP mutants displaying a distinctive monopolar spindle phenotype. It has been postulated that cryptic TOG domains underlie CLASP’s ability regulate MT dynamics. Here, we report the crystal structure of...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2013
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3731388/ https://ncbi.nlm.nih.gov/pubmed/23727231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.04.018 |
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